The centre is located on the corner of Albert Rd and Clarendon St, South Melbourne, directly opposite Albert Park Lake (Bob Jane Stadium), the home of the Melbourne Grand Prix
Traveling by tram, catch the 112 South Melbourne and St Kilda Beach tram and get off at Tram Stop Number 130 on the corner of Clarendon St and Albert Rd.
- Traveling from the Melbourne CBD, drive straight down Spencer Street, which becomes Clarendon Street and intersects with Albert Rd.
- Traveling from St Kilda, drive along either Cantebury Rd or Beaconsfield Pde and turn right into Albert Rd.
- Traveling from the Eastern Corridor, drive down the Kingsway and turn into Albert Rd.
Parking for patients of the Centre for Musculoskeletal Medicine is available in local streets and there is a service road directly outside the centre. Enter through Cecil Street and turn into the service road on Albert Road. Five free one parking spots are located directly opposite the clinic.